Bone Abstracts

see PP290....

Introduction: Recent data suggest that lipid metabolism imbalances affect osteoblast and osteoclast function resulting in altered bone mass quality and quantity. Here we investigated the role of apolipoprotein A-I (apoA-I), key-element in HDL biogenesis in the pathogenesis of osteoporosis in mice.Materials and methods: Lumbar vertebrae and femora from apoA-I deficient (ApoA-I−/−) and WT (ApoA-I<s...